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Quercetin Boosts Pulsatile Gonadotropin-Releasing Hormone Release to Improve Luteal Function via Inhibiting NF-κB/NLRP3-Mediated Neuron Pyroptosis
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-11-03 , DOI: 10.1002/mnfr.202400649
Yujie Shang, Di Han, Kun Deng, Huifang Zhou, Minghua Wu

Scope: Luteal phase deficiency (LPD) is the main cause of infertility without an effective cure. Quercetin (QUE) is a bioactive flavonoid with antioxidant properties, while its role in treating LPD remains unclear. This study aims to investigate the therapeutic effects of QUE on infertility and menstrual disorders induced by LPD, thus further exploring the underlying mechanism.

中文翻译:


槲皮素通过抑制 NF-κB/NLRP3 介导的神经元焦亡促进搏动性促性腺激素释放激素释放以改善黄体功能



范围: 黄体期缺陷 (LPD) 是没有有效治愈方法的不孕症的主要原因。槲皮素 (QUE) 是一种具有抗氧化特性的生物活性类黄酮,但其在治疗 LPD 中的作用尚不清楚。本研究旨在探讨 QUE 对 LPD 诱导的不孕症和月经紊乱的治疗效果,从而进一步探讨其潜在机制。
更新日期:2024-11-03
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