Phytase supplementation is widely used throughout the world for enhancing nutrient use efficiencies in pigs, while added chromium has been shown to help stabilize glucose metabolism by enhancing insulin sensitivity. Therefore, the objectives of this metabolism study were to examine the potential synergies of these additives to see if nutrient digestibilities and/or blood metabolites could be improved in grower pigs. A total of 12 Genesus terminal genetics grower pigs (20.7 kg) were allotted randomly in a crossover experiment with 4 periods and 4 dietary treatments based on a 2 × 2 factorial design via 2 groups. This provided 12 replicates per dietary treatment. Treatment (Trt) 1 consisted of a control diet without phytase while Trt 2 had decreased levels of soybean meal, calcium (Ca) and phosphorus (P) with added phytase (1,500 phytase units (FYT)/kg, HiPhorius; dsm-firmenich, Plainsboro, NJ). The nutrient release values for amino acids, calcium and phosphorus were via standard recommendations from dsm-firmenich for the phytase. Treatment 3 consisted of the control diet without phytase with 200 parts per billion (ppb) of added chromium from chromium tripicolinate (Chromax, Kent Nutrition Group, Inc., Muscatine, IA) while Trt 4 consisted of the diets with decreased levels of soybean meal, Ca and P with added HiPhorius (1,500 FYT/kg) and Chromax (200 ppb). With 6 metabolism crates available, 4, 1-wk-long periods were utilized to evaluate each of the 4 treatments with each pig with 2 groups evaluated and pooled for data analysis. The pigs were allowed a 4-d acclimation period followed by a 3-d collection period with the experimental diets fed at 4% body weight each day. Water was administered to each pig at 2.5 times the amount of feed fed each day. On the last day of the collection period, blood samples were collected before the meal (fasting) and then 2 h after the meal (postprandial). There were no significant differences among treatments for both fasting and postprandial glucose and insulin levels. Added phytase resulted in a reduction (P < 0.05) in fasting blood urea nitrogen (N). Nitrogen digestibility and retention and dry matter (DM) digestibility were all improved (P < 0.01) with pigs fed supplemental phytase. Supplemental chromium was without effect on any of the N and DM digestibility measurements. These data suggest that supplemental phytase has positive effects on improving N and DM digestibilities.

中文翻译：

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补充植酸酶和/或三吡啶啶酸铬对生长猪干物质和氮消化率以及血液代谢物的疗效


植酸酶补充剂在世界范围内被广泛用于提高猪的营养利用效率，而添加的铬已被证明可以通过增强胰岛素敏感性来帮助稳定葡萄糖代谢。因此，这项代谢研究的目的是检查这些添加剂的潜在协同作用，以了解是否可以改善生长猪的营养消化率和/或血液代谢物。在交叉实验中，共有 12 头 Genesus 终末遗传学生长猪（20.7 公斤）被随机分配，基于 2 组的 2 × 2 因子设计，分为 4 个时期和 4 个饮食处理。这为每种饮食处理提供了 12 次重复。处理 （Trt） 1 包括不含植酸酶的对照饮食，而 Trt 2 添加植酸酶后豆粕、钙 （Ca） 和磷 （P） 水平降低 （1,500 植酸酶单位 （FYT）/kg，HiPhorius;dsm-firmenich，新泽西州普兰斯伯勒）。氨基酸、钙和磷的营养物质释放值是根据 dsm-firmenich 对植酸酶的标准建议得出的。处理 3 包括不含植酸酶的对照饮食，添加十亿分之 200 （ppb） 的三氯胆酸铬（Chromax，Kent Nutrition Group， Inc.，马斯卡廷，爱荷华州），而 Trt 4 包括豆粕、Ca 和 P 水平降低的饮食，添加 HiPhorius （1,500 FYT/kg） 和 Chromax （200 ppb）。在 6 个代谢箱可用的情况下，使用 4 个 1 周长的周期来评估每头猪的 4 种处理中的每一种，其中 2 组进行评估并合并用于数据分析。猪被允许 4 天驯化期，然后是 3 天收集期，实验日粮每天以 4% 的体重喂养。每头猪的饮水量为每天饲喂量的 2.5 倍。 在采集期的最后一天，餐前 （禁食） 采集血样，然后在餐后 2 小时 （餐后） 采集血样。空腹和餐后血糖和胰岛素水平的治疗之间没有显著差异。添加植酸酶导致空腹血尿素氮 （N） 降低 （P < 0.05）。补充植酸酶的猪的氮消化率和保留率以及干物质 （DM） 消化率均得到改善 （P < 0.01）。补充铬对任何 N 和 DM 消化率测量都没有影响。这些数据表明，补充植酸酶对提高 N 和 DM 消化率有积极影响。