listing transplanted January 1st, 2010, to May 31st, 2022 (N=9,178) were included from the Scientific Registry of Transplant Recipients. Recipients were stratified into three groups according to Material Community Deprivation Index score, with greater score representing higher neighborhood socioeconomic deprivation. Outcomes were modeled using multivariable logistic regression and Cox proportional hazards models. Results: Twenty-four percent (N=110) of recipients from neighborhoods of high socioeconomic deprivation identified as being of Black race, versus 12% (N=383) of recipients from neighborhoods of low socioeconomic deprivation. Neighborhoods of high socioeconomic deprivation had a much greater proportion of recipients identifying as being of Hispanic ethnicity (67%, N=311), versus neighborhoods of low socioeconomic deprivation (17%, N=562). The hazard of graft loss was 55% higher (aHR 1.55, 95% CI: 1.24, 1.94) for recipients from neighborhoods of high versus recipients from low socioeconomic deprivation neighborhoods when adjusted for base covariates, race and ethnicity, and insurance status, with 59% lower odds (aOR 0.41, 95% CI: 0.30, 0.56) of living donor transplantation and, although not statistically significant, 8% lower odds (aOR 0.92, 95% CI: 0.72, 1.19) of preemptive transplantation. The hazard of graft loss was 41% higher (aHR 1.41, 95% CI: 1.25, 1.60) for recipients from neighborhoods of intermediate versus recipients from low socioeconomic deprivation neighborhoods when adjusted for base covariates, race and ethnicity, and insurance status, with 27% lower odds (aOR 0.73, 95% CI: 0.66, 0.81) of living donor transplantation and 11% lower odds (aOR 0.89, 95% CI: 0.80, 0.99) of preemptive transplantation. Conclusions: Children from neighborhoods of high socioeconomic deprivation have worse graft survival and lower utilization of preemptive and living donor transplantation. These findings demonstrate inequities in pediatric kidney transplantation that warrant further intervention. Copyright © 2024 by the American Society of Nephrology...

中文翻译：

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社区社会经济剥夺与儿科肾移植受者较差的结果相关


2010 年 1 月 1 日至 2022 年 5 月 31 日移植的列表 （N=9,178） 被纳入移植受者科学登记处。根据物质社区剥夺指数得分，接受者分为三组，得分越高代表社区社会经济剥夺程度越高。使用多变量 logistic 回归和 Cox 比例风险模型对结果进行建模。结果：来自社会经济高度剥夺社区的 24% （N=110） 接受者被确定为黑人，而来自社会经济低剥夺社区的接受者为 12% （N=383）。与社会经济贫困程度低的社区 （17%，N=562） 相比，社会经济剥夺程度高的社区认为是西班牙裔的接受者比例要高得多 （67%，N=311）。当调整基本协变量、种族和民族以及保险状况时，来自高社会经济剥夺社区的受者与来自低社会经济剥夺社区的受者相比，移植物丢失的风险高 55% （aOR 0.41， 95% CI： 1.24， 1.94），活体供体移植的几率低 59% （aOR 0.41， 95% CI： 0.30， 0.56），虽然没有统计学意义， 抢先移植的几率降低 8% （aOR 0.92， 95% CI： 0.72， 1.19）。当调整基本协变量、种族和民族以及保险状况时，来自中等社区的受者与来自低社会经济剥夺社区的受者相比，移植物丢失的风险高 41% （aOR 0.73， 95% CI： 1.25， 1.60），活体供体移植的几率低 27% （aOR 0.73， 95% CI： 0.66， 0.81），比值低 11% （aOR 0.89， 95% CI： 0.80， 0.99） 的抢先性移植。 结论： 来自社会经济高度贫困社区的儿童移植物存活率较差，抢先和活体供体移植的利用率较低。这些发现表明小儿肾移植中存在不平等，需要进一步干预。美国肾脏病学会版权所有 © 2024...