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Near-infrared SPR biosensor based on photonic crystal fiber for DNA hybridization detection
Analytica Chimica Acta ( IF 5.7 ) Pub Date : 2024-11-01 , DOI: 10.1016/j.aca.2024.343385
Zhiyong Yin, Zhibing Zhang, Xili Jing, Linchuan Hu, Shuguang Li, Jianshe Li

Surface plasmon resonance (SPR) sensing technology has been widely used in biometrics, but the weak detection capability and low sensitivity limit the development of SPR biosensors. In this work, we propose to employ the transition metal disulfide (TMD) material MoS2 to induce the SPR effect into the near-infrared band. The aim of this work is to develop a near-infrared sensor capable of quantitatively detecting the concentration of cDNA, which is able to solve the problems of low sensitivity, parameter crosstalk and so on.

中文翻译:


基于光子晶体光纤的近红外 SPR 生物传感器用于 DNA 杂交检测



表面等离子体共振 (SPR) 传感技术在生物识别技术中得到了广泛的应用,但检测能力弱、灵敏度低限制了 SPR 生物传感器的发展。在这项工作中,我们建议使用过渡金属二硫化物 (TMD) 材料 MoS2 在近红外波段诱导 SPR 效应。这项工作的目的是开发一种能够定量检测 cDNA 浓度的近红外传感器,能够解决灵敏度低、参数串扰等问题。
更新日期:2024-11-01
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