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TAM-ing the beast with IL-34 blockade
Science Immunology ( IF 17.6 ) Pub Date : 2024-11-01 , DOI: 10.1126/sciimmunol.adu0981
Aron Gyorgypal, Robert M. Anthony

TP53 mutation triggers IL-34 secretion by cancer stem cells, reprogramming macrophages to suppress T cells and promote tumor immune escape.

中文翻译:


用 IL-34 阻断剂驯服野兽



TP53 突变触发癌症干细胞分泌 IL-34,对巨噬细胞进行重编程以抑制 T 细胞并促进肿瘤免疫逃逸。
更新日期:2024-11-01
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