Background

We sought to determine whether various ion scanner devices could provide a practical alternative in field-based research, where affordable and accessible drug screening is needed for comprehensive and ongoing investigation.

Methods

In Study 1, off-site sample analysis proved inconclusive, rendering Protocols A and B impractical for ongoing drug screening. Conversely, Study 2’s on-site, real-time analysis (Protocol C) emerged as a more effective method. The Itemizer3, particularly in Protocol C, excelled in discerning drug users. Comparing admitted drug use rates in both studies, the mere presence of an objective measure, confirmational or not, likely facilitated more truthful participant responses, highlighting the efficacy of real-time, on-site drug screening using IMS/ITMS technologies.

Findings

All samples analyzed off-site in Study 1 were found to be inconclusive. As such, Protocols A and B were not feasible for on-going drug screening and monitoring. Conversely, the results of Study 2 Protocol C demonstrated that harvesting samples directly off participants on-site and analyzing these in-real time to be a more efficacious method. Our findings in Protocol C also show that the Itemizer3 was better at identifying those who did not use drugs from those who did. Looking at the incidence rates of admitted drug use in Studies 1 and 2, we find that simply having an objective measure present (irrespective of whether it is confirmational or not) likely resulted in us obtaining more truthful responses from participants about their use of drugs.

Conclusions

Our results underscore IMS/ITMS practicality for on-site NED drug screening.

中文翻译：

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检查夜间娱乐区毒品筛查技术的使用

 背景

我们试图确定各种离子扫描仪设备是否可以在基于现场的研究中提供一种实用的替代方案，其中需要负担得起且可获得的药物筛选以进行全面和持续的调查。

 方法

在研究 1 中，场外样本分析被证明没有结论，这使得方案 A 和 B 对于正在进行的药物筛选不切实际。相反，研究 2 的现场实时分析（方案 C）成为一种更有效的方法。Itemizer3，特别是在协议 C 中，在识别吸毒者方面表现出色。比较两项研究中入院的药物使用率，仅存在客观指标（确认性或否）可能有助于更真实的参与者反应，突出了使用 IMS/ITMS 技术进行实时现场药物筛查的有效性。

 发现

在研究 1 中发现所有场外分析的样本均不确定。因此，方案 A 和 B 对于正在进行的药物筛选和监测是不可行的。相反，研究 2 方案 C 的结果表明，直接在现场从参与者身上采集样本并实时分析这些样本是一种更有效的方法。我们在方案 C 中的研究结果还表明，Itemizer3 更擅长从使用药物的人中识别出不使用药物的人。查看研究 1 和 2 中入院吸毒的发生率，我们发现，简单地存在一个客观的衡量标准（无论它是否是确认性的）可能会导致我们从参与者那里获得关于他们使用药物的更真实的回答。

 结论

我们的结果强调了 IMS/ITMS 在现场 NED 药物筛选中的实用性。