Individual differences in reward functioning have been associated with numerous disorders in adolescence. Given relations with multiple forms of psychopathology, it is unclear whether these associations are disorder specific or reflective of shared variance across multiple disorders. In a sample of adolescents (N = 418), we examined associations between neural and self-reported indices of early reward functioning (age 12) with different levels of a hierarchical psychopathology model assessed later in adolescence (age 18). We examined whether prospective relationships between reward functioning are specific to individual disorders or better explained by transdiagnostic dimensions. We found modest results for prospective associations between reward indices and different dimensions of psychopathology, with most significant associations not surviving correction for multiple comparisons. We discuss the benefits and limitations of the modeling approach used to examine dimension-specific associations that future work can build on. Overall, more work is needed to better understand how reward functioning is specifically associated with different forms of and hierarchical levels of psychopathology. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

中文翻译：

---

早期青少年奖励功能与后来的精神病理学维度之间的预期关联。


奖励功能的个体差异与青春期的许多疾病有关。鉴于与多种形式的精神病理学的关系，尚不清楚这些关联是疾病特异性的还是反映了多种疾病的共同差异。在青少年样本 （N = 418） 中，我们检查了早期奖励功能 （12 岁） 的神经和自我报告指标与青春期后期 （18 岁） 评估的不同层次精神病理学模型之间的关联。我们研究了奖励功能之间的前瞻性关系是特定于个体疾病的，还是通过跨诊断维度更好地解释。我们发现奖励指数与精神病理学不同维度之间的预期关联结果适中，大多数显著关联在多重比较的校正中未幸存下来。我们讨论了用于检查未来工作可以建立的特定于维度的关联的建模方法的优点和局限性。总的来说，需要更多的工作来更好地了解奖励功能如何与不同形式和等级水平的精神病理学具体相关。（PsycInfo 数据库记录 （c） 2024 APA，保留所有权利）。