To end AIDS as a public health threat by 2030, we must leverage both the impactful message of U=U (undetectable equals untransmittable) and viral suppression to improve the wellbeing of individuals living with HIV, increase engagement with HIV services, and reduce barriers such as stigma, discrimination, and criminalisation. This message requires clear and unambiguous evidence-based narratives that emphasise the message that there is zero risk of sexual transmission when an undetectable viral load is maintained and negligible risk when viral suppression (as defined by 200–1000 copies per mL) is maintained. Dissemination of this information to individuals living with or affected by HIV, health-care workers, communities, the general public, and policy makers will increase awareness and credibility of this message and challenge deep-seated misperceptions. Furthermore, understanding the impact of this evidence underscores the necessity to urgently prioritise universal access to quality care, including viral load testing; leverage community leadership to address structural barriers; and monitor for ongoing success. Responsible and equitable messaging, which includes attention to women and marginalised groups, should be used to realise benefits for personal wellbeing and work towards an AIDS-free future.

中文翻译：

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终结艾滋病作为公共卫生威胁：必须明确传递 U=U 信息、病毒抑制和零风险


为了到 2030 年消除艾滋病作为公共卫生威胁，我们必须利用 U=U（检测不到等于无法传播）的有影响力信息和病毒抑制来改善 HIV 感染者的福祉，增加对 HIV 服务的参与，并减少污名化、歧视和刑事定罪等障碍。该信息需要清晰明确的循证叙述，强调当维持无法检测的病毒载量时，性传播的风险为零，而当维持病毒抑制（定义为每毫升 200-1000 个拷贝）时，性传播的风险可以忽略不计。将这些信息传播给 HIV 感染者或受其影响的个人、卫生保健工作者、社区、公众和政策制定者，将提高对这一信息的认识和可信度，并挑战根深蒂固的误解。此外，了解这些证据的影响强调了紧急优先考虑普遍获得优质护理的必要性，包括病毒载量检测;利用社区领导来解决结构性障碍;并监控持续的成功。应利用负责任和公平的信息传递，包括对妇女和边缘化群体的关注，来实现个人福祉的利益，并努力实现无艾滋病的未来。