Tissue-like bioelectronics have emerged as practical, user-friendly and unobtrusive systems for seamless bidirectional integration with the human body. Two-dimensional materials, being led by the prototypical graphene, uniquely fit the task of creating ultrathin and functional interfaces with biological matter. In this Perspective, we comprehensively discuss 2D materials and their electrical, optical, environmental and mechanical properties relevant to bioelectronics. We present examples of 2D material-based bioelectronic devices for tissue interfacing (skintronics) and organ interfacing (organtronics). Importantly, we provide a roadmap for the future development of the field and highlight associated challenges yet to be solved.

组织状生物电子学已成为实用、用户友好且不引人注目的系统，可与人体无缝双向整合。以原型石墨烯为主导的二维材料独特地适合于与生物物质创建超薄和功能界面的任务。在这个观点中，我们全面讨论了 2D 材料及其与生物电子学相关的电学、光学、环境和机械特性。我们介绍了用于组织接口 （skintronics） 和器官接口 （organtronics） 的基于 2D 材料的生物电子设备的示例。重要的是，我们为该领域的未来发展提供了路线图，并强调了尚未解决的相关挑战。