Harrold et al. evaluate the fertility impact of checkpoint inhibitor blockade (ICB), demonstrating that unlike in utero exposure, post-exposure conception appears to result in uncomplicated pregnancies and healthy progeny. They demonstrate contemporaneous monitoring of temporal female hormonal fluctuations before, on, and post ICB exposure and prior to successful embryo implantation.

中文翻译：

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免疫检查点抑制剂暴露后的生育结果


Harrold 等人评估了检查点抑制剂阻断 （ICB） 对生育能力的影响，表明与子宫内暴露不同，暴露后受孕似乎会导致无并发症的怀孕和健康的后代。他们展示了在 ICB 暴露之前、期间和之后以及胚胎成功植入之前对颞部女性荷尔蒙波动的同期监测。