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Advantages of dimethyl carbonate as organic modifier for enantioseparation of novel psychoactive substances in sub/supercritical fluid chromatography
Analytica Chimica Acta ( IF 5.7 ) Pub Date : 2024-10-31 , DOI: 10.1016/j.aca.2024.343380
Denisa Folprechtová, Elisabeth Seibert, Martin G. Schmid, Květa Kalíková

Sub/supercritical fluid chromatography is regarded as a greener separation technique due to the use of carbon dioxide as the main component of the mobile phase compared to conventional liquid chromatography techniques. Organic co-solvents are usually added to carbon dioxide to increase elution strength of the mobile phase. Therefore, it is of great importance to test applicability of green co-solvents in separation methods and to include them among commonly used mobile phase components.

中文翻译:


碳酸二甲酯作为有机改性剂在亚/超临界流体色谱法中对映体分离新型精神活性物质的优势



亚/超临界流体色谱被认为是一种更环保的分离技术,因为与传统液相色谱技术相比,亚/超临界流体色谱使用二氧化碳作为流动相的主要成分。通常将有机助溶剂添加到二氧化碳中,以提高流动相的洗脱强度。因此,测试绿色助溶剂在分离方法中的适用性并将其包含在常用的流动相组分中非常重要。
更新日期:2024-10-31
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