Human papillomavirus (HPV)-based cervical screening is a globally recommended public health policy. Randomised clinical trials find superior performance of primary HPV-based screening compared with cytology for preventing cervical cancer. However, additional evidence from real-world public health policies is needed. In preplanned secondary analysis of a randomised health-care policy trial in Sweden we aimed to evaluate which policy provided better protection against invasive cervical cancer, after two full rounds of screening.

中文翻译：

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基于人瘤病毒的宫颈筛查和长期宫颈癌风险： 瑞典的一项随机医疗保健政策试验


基于人瘤病毒 （HPV） 的宫颈筛查是全球推荐的公共卫生政策。随机临床试验发现，与细胞学筛查相比，基于原发性 HPV 的筛查在预防宫颈癌方面的性能更优。然而，需要来自现实世界公共卫生政策的额外证据。在瑞典一项随机医疗保健政策试验的预先计划的二次分析中，我们旨在评估在两轮完整筛查后，哪种政策能更好地预防浸润性宫颈癌。