A nonsense mutation in TBC1D4 has previously been associated with hyperinsulinaemia and increased risk of type 2 diabetes mellitus. A new report shows that carriers have isolated muscle insulin resistance that improves after an acute bout of exercise.

中文翻译：

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急性运动对 TBC1D4 突变携带者的影响


TBC1D4 中的无义突变以前与高胰岛素血症和 2 型糖尿病风险增加有关。一份新报告显示，携带者有孤立的肌肉胰岛素抵抗，这种抵抗在急性运动后有所改善。