Although pharmacological effects of SGLT2 inhibitors on the development of frailty and sarcopenia were known, the role of SGLT1 remained less clear. The present study investigated the possible effect of SGLT1 inhibition on these conditions and explored potential mediators.

中文翻译：

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SGLT1 抑制对虚弱和肌肉减少症的影响：一项介导孟德尔随机化研究


尽管已知 SGLT2 抑制剂对虚弱和肌肉减少症发展的药理作用，但 SGLT1 的作用仍不清楚。本研究调查了 SGLT1 抑制对这些情况的可能影响，并探讨了潜在的介质。