Quinoxaline is a chemical moiety known for its diverse physicochemical and biological properties, making it the focus of extensive research. Over the past few decades, quinoxaline scaffolds have been utilized in the design and development of various bioactive molecules, dyes, fluorescent materials, electroluminescent materials, organic sensitizers for solar cells, and polymeric optoelectronic materials. Herein, we present a metal‐free and rapid protocol for the phosphorylation of quinoxalines and quinoxalin‐2(1H)‐one. This method employs oxygen as an oxidant under ambient temperature and atmospheric pressure, with experimental evidence indicating the absence of radical involvement. Our methodology provides range of phosphorylated quinoxalines and quinoxaline‐2(1H)‐one in yields ranging from 47% to 99%.

中文翻译：

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酸介导的喹喔啉和喹喔啉-2（1H）-one 的氧化 C-H 磷酸化


喹喔啉是一种化学部分，以其多种物理化学和生物特性而闻名，使其成为广泛研究的重点。在过去的几十年里，喹喔啉支架已被用于各种生物活性分子、染料、荧光材料、电致发光材料、太阳能电池有机敏化剂和聚合物光电材料的设计和开发。在此，我们提出了一种用于喹喔啉和喹喔啉-2（1H）-one 磷酸化的无金属快速方案。该方法在环境温度和大气压下使用氧气作为氧化剂，实验证据表明没有自由基参与。我们的方法提供了磷酸化喹啉和喹喔啉-2（1H）-one，产量范围为 47% 至 99%。