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Evaluating culture-free targeted next-generation sequencing for diagnosing drug-resistant tuberculosis: a multicentre clinical study of two end-to-end commercial workflows
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2024-10-29 , DOI: 10.1016/s1473-3099(24)00586-3 Rebecca E Colman PhD, Marva Seifert PhD, Andres De la Rossa PhD, Sophia B Georghiou PhD, Christine Hoogland PhD, Swapna Uplekar PhD, Sacha Laurent PhD, Camilla Rodrigues MD, Priti Kambli PhD, Nestani Tukvadze MD, Nino Maghradze PhD, Shaheed V Omar PhD, Lavania Joseph MSc, Anita Suresh MBA, Timothy C Rodwell PhD MD
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2024-10-29 , DOI: 10.1016/s1473-3099(24)00586-3 Rebecca E Colman PhD, Marva Seifert PhD, Andres De la Rossa PhD, Sophia B Georghiou PhD, Christine Hoogland PhD, Swapna Uplekar PhD, Sacha Laurent PhD, Camilla Rodrigues MD, Priti Kambli PhD, Nestani Tukvadze MD, Nino Maghradze PhD, Shaheed V Omar PhD, Lavania Joseph MSc, Anita Suresh MBA, Timothy C Rodwell PhD MD
Drug-resistant tuberculosis remains a major obstacle in ending the global tuberculosis epidemic. Deployment of molecular tools for comprehensive drug resistance profiling is imperative for successful detection and characterisation of tuberculosis drug resistance. We aimed to assess the diagnostic accuracy of a new class of molecular diagnostics for drug-resistant tuberculosis.
中文翻译:
评估无培养靶向下一代测序诊断耐药结核病:两个端到端商业工作流程的多中心临床研究
耐药结核病仍然是终结全球结核病流行的主要障碍。部署分子工具进行全面的耐药性分析对于成功检测和表征结核病耐药性至关重要。我们旨在评估一类新的耐药结核病分子诊断的准确性。
更新日期:2024-10-29
中文翻译:

评估无培养靶向下一代测序诊断耐药结核病:两个端到端商业工作流程的多中心临床研究
耐药结核病仍然是终结全球结核病流行的主要障碍。部署分子工具进行全面的耐药性分析对于成功检测和表征结核病耐药性至关重要。我们旨在评估一类新的耐药结核病分子诊断的准确性。