The classification of cardiogenic shock (CS) has evolved from a singular cold-and wet-hemodynamic profile. Data from registries and clinical trials have contributed to a broader recognition that although all patients with CS have insufficient cardiac output leading to end organ hypoperfusion, there is considerable variability in CS acuity, underlying etiologies, volume status, and systemic vascular resistance. Mixed CS can be broadly categorized as CS with at least 1 additional shock state. Mixed CS states are now the second leading cause of shock in contemporary coronary intensive care units, but there is little high-quality evidence to guide routine care, and there are no standardized classification frameworks or well-established hemodynamic definitions. This primer summarizes the current epidemiology and proposes a classification framework and invasive hemodynamic parameters to guide categorization that could be applied to help better phenotype patients captured in registries and trials, as well as guide management of mixed CS states.

中文翻译：

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混合性心源性休克：标准化分类、血流动力学定义和管理框架的建议。


心源性休克 （CS） 的分类是从单一的冷湿血流动力学特征演变而来的。来自登记处和临床试验的数据有助于更广泛地认识到，尽管所有 CS 患者的心输出量不足导致终末器官灌注不足，但 CS 急性度、潜在病因、容量状态和全身血管阻力存在相当大的差异。混合型 CS 可大致归类为至少具有 1 种额外休克状态的 CS。混合性 CS 状态现在是当代冠状动脉重症监护病房休克的第二大原因，但几乎没有高质量的证据来指导常规护理，也没有标准化的分类框架或完善的血流动力学定义。本入门指南总结了当前的流行病学，并提出了一个分类框架和侵入性血流动力学参数来指导分类，这些分类可用于帮助在登记和试验中捕获更好的表型患者，以及指导混合 CS 状态的管理。