Synthesis and characterization of new macrolones — fusions of two antibiotic classes with distinct bacterial targets — reveal the basis for their activity and potential design principles that may help combat development of antimicrobial resistance.

中文翻译：

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在双倍处躲避阻力


新大环酮类药物（具有不同细菌靶标的两种抗生素类别的融合）的合成和表征揭示了其活性的基础和可能有助于对抗抗菌素耐药性发展的潜在设计原则。