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Patient‐reported outcomes, postoperative pain and pain relief after day case surgery (POPPY): methodology for a prospective, multicentre observational study*
Anaesthesia ( IF 7.5 ) Pub Date : 2024-10-29 , DOI: 10.1111/anae.16460
William M. Hare, Martha Belete, Adam B. Brayne, Harriet Daykin, Matthew Everson, Anna Ratcliffe, Katie Samuel, Lexy Sorrell, Mark Rockett

SummaryBackgroundIn the UK, approximately 70% of surgical procedures are undertaken as day‐cases. Little information exists about recovery from day‐case surgery, yet international data highlights patients are at risk of developing significant longer‐term health problems including chronic post‐surgical pain and persistent postoperative opioid use. The Patient‐reported Outcomes, Postoperative Pain and pain relief after daY case surgery (POPPY) study was a national prospective multicentre observational study, measuring short‐ and longer‐term patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery.MethodsThis was a collaborative project led by resident anaesthetists under the Research and Audit Federation of Trainees umbrella. Adult day‐case surgical patients were recruited on the day of surgery. Baseline data including patient characteristics; procedure details; pre‐operative analgesic use; pre‐existing pain; and quality of life scores were recorded. Patients were followed up through automated short message service messages. Short‐term (postoperative days 1, 3 and 7) outcomes included: quality of recovery; pain severity; impact of pain on function; and analgesic use. Longer‐term outcomes (postoperative day 97) included: quality of life; analgesic use; incidence of chronic post‐surgical pain; and incidence persistent postoperative opioid use. Additional outcomes were completed by those patients with chronic post‐surgical pain and persistent postoperative opioid use, with 30 patients recruited to a qualitative semi‐structured interview study exploring postoperative expectations, recovery, postoperative pain and opioid use.ResultsAn embedded pilot study at four sites recruited 129 patients. Responses to the automated short message service were gained from 129 patients (100%) at day 1; 116 (89.9%) at day 3; 108 (83.7%) at day 7; and 77 (59.7%) at day 97 postoperatively. The pilot enabled refinement of the methods and processes before the national roll out.ConclusionThis paper outlines the methods for the POPPY study, the largest UK multicentre prospective observational study considering short‐ and longer‐term outcomes following day‐case surgery.

中文翻译:


患者报告的结果、术后疼痛和日间病例手术后疼痛缓解 (POPPY):前瞻性、多中心观察性研究的方法*



摘要背景在英国,大约 70% 的外科手术是作为日间病例进行的。关于日间手术恢复的信息很少,但国际数据强调患者有出现重大长期健康问题的风险,包括慢性术后疼痛和术后持续使用阿片类药物。患者报告的结果、术后疼痛和 daY 病例手术后疼痛缓解 (POPPY) 研究是一项全国性前瞻性多中心观察性研究,测量患者报告的短期和长期结果、术后疼痛和日间手术后疼痛缓解。方法这是由住院麻醉师在实习生研究和审计联合会旗下领导的合作项目。在手术当天招募成年日间手术患者。基线数据,包括患者特征;程序详细信息;术前镇痛药的使用;预先存在的疼痛;并记录生活质量评分。通过自动短信服务消息对患者进行随访。短期(术后第 1 天、第 3 天和第 7 天)结局包括:恢复质量;疼痛严重程度;疼痛对功能的影响;和镇痛药的使用。长期结果(术后第 97 天)包括:生活质量;使用镇痛药;慢性术后疼痛的发生率;和术后持续使用阿片类药物的发生率。那些患有慢性术后疼痛和术后持续使用阿片类药物的患者完成了额外的结局,招募了 30 名患者参加一项定性半结构化访谈研究,探讨术后预期、恢复、术后疼痛和阿片类药物的使用。结果在 4 个地点进行的一项嵌入式试点研究招募了 129 名患者。 第 1 天有 129 名患者 (100%) 对自动短信服务的反应;第 3 天 116 例 (89.9%);第 7 天 108 例 (83.7%);术后第 97 天 77 例 (59.7%)。该试点项目在全国推广之前对方法和流程进行了改进。结论本文概述了 POPPY 研究的方法,这是英国最大的多中心前瞻性观察研究,考虑了日间手术后的短期和长期结果。
更新日期:2024-10-29
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