Chiral separation is of great significance but remains challenging in analytical chemistry. Chiral stationary phase based high-performance liquid chromatography (HPLC) is regarded as one of the most effective and widely used methods for chiral resolution. Microporous organic networks (MONs) are an emerging class of porous materials with designable topology, large surface area, abundant micropores, and excellent stabilities that have attracted tremendous interests in chromatographic separation. However, the usage of chiral MONs as chiral stationary phases for chiral HPLC separation has not been reported so far.

中文翻译：

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用于手性高效液相色谱分离的手性微孔有机网络的“Click”后合成


手性分离具有重要意义，但在分析化学中仍然具有挑战性。基于手性固定相的高效液相色谱 （HPLC） 被认为是最有效和广泛使用的手性分离方法之一。微孔有机网络 （MON） 是一类新兴的多孔材料，具有可设计的拓扑结构、大表面积、丰富的微孔和出色的稳定性，在色谱分离领域引起了极大的兴趣。然而，到目前为止，尚未报道将手性 MON 用作手性 HPLC 分离的手性固定相。