ObjectiveThe objective of this study was to compare open versus closed healing of soft and hard tissue following alveolar ridge preservation (ARP) procedures in damaged extraction sockets.Materials and MethodsARP was performed in five mongrel dogs using collagenated deproteinized bovine bone mineral (cDBBM) and a resorbable non‐cross‐linked collagen membrane (NCCM) in damaged extraction sockets, with each socket entrance left either open (open group) or closed (closed group). Clinical wound epithelization at the socket entrance and the dimensions of keratinized tissue were evaluated over time. Additionally, the augmented ridge dimensions and new bone formation were assessed radiographically and histologically at 8 weeks after surgery.ResultsThe dimensions of the socket entrance gradually decreased in the open group, and wound epithelization was almost complete within 4 weeks. The mucogingival junction was maintained more apically in the open group than in the closed group (0.14 ± 0.40 mm vs. −0.86 ± 0.71 mm [mean ± SD], p < 0.05). The augmented ridge dimensions did not differ significantly between the open and closed groups (93.1% ± 5.4% vs. 88.3% ± 11.2%, p > 0.05). Histological analyses revealed no significant differences in the amount of newly formed bone. However, membrane resorption in the crestal region was more pronounced in the open group.ConclusionOpen and closed healing approaches for ARP in extraction sockets with damaged buccal wall resulted in similar ridge dimensions and new bone formation. However, there was less reduction of the buccal bone crest and wider keratinized tissue width after open healing.

中文翻译：

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受损拔牙窝中开放愈合与闭合愈合的牙槽嵴再生：一项临床前体内研究


目的本研究的目的是比较受损拔牙窝中牙槽嵴保留 （ARP） 手术后软组织和硬组织的开放愈合与闭合愈合。材料和方法在受损的提取窝中使用胶原脱蛋白牛骨矿物质 （cDBBM） 和可吸收的非交联胶原膜 （NCCM） 对 5 只犬进行 ARP，每个窝入口保持开放（开放组）或闭合（封闭组）。随着时间的推移评估了窝入口处的临床伤口上皮化和角化组织的尺寸。此外，在手术后 8 周进行放射学和组织学评估增加的嵴尺寸和新骨形成。结果开放组窝入口尺寸逐渐减小，伤口上皮化在 4 周内几乎完全。开放组比封闭组更能保持粘膜龈交界处 （0.14 ± 0.40 mm vs. -0.86 ± 0.71 mm [平均值 ± SD]，p < 0.05）。开放组和封闭组之间的增大脊尺寸没有显著差异 （93.1% ± 5.4% vs. 88.3% ± 11.2%，p > 0.05）。组织学分析显示新形成的骨量没有显著差异。然而，开放组牙槽嵴区的膜吸收更为明显。结论颊壁受损的拔牙窝中 ARP 的开放和封闭愈合方法导致相似的嵴尺寸和新的骨形成。然而，开放愈合后颊骨嵴的减少较少，角化组织宽度变宽。