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A Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery.
Anesthesia & Analgesia ( IF 4.6 ) Pub Date : 2024-10-25 , DOI: 10.1213/ane.0000000000007218
Bin Gu,Zhang-Xiang Huang,Hui-Dan Zhou,Yan-Hong Lian,Shuang He,Meng Ge,Hui-Fang Jiang

BACKGROUND The interpectoral-pectoserratus plane block is expected to anesthetize the lateral breast, but it is unclear whether the deep parasternal intercostal plane block may enhance recovery by providing analgesia to the medial breast. METHODS Patients undergoing breast cancer surgery were randomly assigned to receive either the interpectoral-pectoserratus block (single block) or interpectoral-pectoserratus combined with deep parasternal intercostal block (combined block). The primary outcome was the quality of recovery-15 questionnaire score assessed at 24 hours postoperatively. Secondary measures included dermatomal block assessment, pain severity, opioid consumption, opioid-related adverse events, hospital length of stay, and chronic postsurgical pain at 3 months after surgery. RESULTS One hundred and sixteen patients were recruited, 58 in the single block group and 58 in the combined block group. There was no important difference in the 24-hour quality of recovery scores with mean (standard deviation [SD]) 123.6 (6.3) in the single block group and 123.2 (7.1) in the combined block group (mean difference, 0.4; 95% confidence interval [CI], -2.0 to 2.9; P =.731). There was greater dermatomal block on medial breast in the combined block group. There were no differences in other secondary outcomes. CONCLUSIONS Addition of deep parasternal intercostal plane block was not superior to interpectoral-pectoserratus plane block alone for the quality of recovery in patients undergoing breast cancer surgery.

中文翻译:


在乳腺癌手术中将深胸骨旁肋间平面阻滞添加到胸侧-胸锯齿平面阻滞的随机对照试验。



背景 胸间-胸锯齿平面阻滞有望麻醉外侧乳房,但目前尚不清楚深胸骨旁肋间平面阻滞是否可以通过为内侧乳房提供镇痛来促进恢复。方法 接受乳腺癌手术的患者被随机分配接受胸间-胸锯齿阻滞 (单块) 或胸间-胸锯齿联合胸骨旁深部肋间阻滞 (联合阻滞)。主要结局是术后 24 小时评估的 recovery-15 问卷评分质量。次要指标包括皮节阻滞评估、疼痛严重程度、阿片类药物消耗、阿片类药物相关不良事件、住院时间和术后 3 个月的慢性术后疼痛。结果 共招募 116 例患者,其中单块组 58 例,联合块组 58 例。24 小时恢复质量评分无显著差异,单组组平均值 (标准差 [SD])为 123.6 (6.3),联合组为 123.2 (7.1) (平均差,0.4;95% 置信区间 [CI],-2.0 至 2.9;P =.731)。联合阻滞组乳房内侧皮节阻滞较大。其他次要结局没有差异。结论 在接受乳腺癌手术的患者恢复质量方面,添加胸骨旁深部肋间平面阻滞并不优于单独使用胸间-胸锯齿平面阻滞。
更新日期:2024-10-25
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