The metalation of dihalogeno and halogenomethoxypyrazines was performed. The resulting pyrazines were submitted to a cross-coupling reaction with propargyl alcohol followed, after dehydration, by a catalytic reduction. This gives a new route to the synthesis of a key intermediate in the synthesis of arglecin.

中文翻译：

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通过吡嗪的金属化和交叉偶联制得arglecin的新途径。二嗪的金属化。十二

进行了二卤代和卤代甲氧基吡嗪的金属化。使所得的吡嗪与炔丙醇进行交叉偶联反应，然后在脱水后，通过催化还原。这为合成arglecin中的关键中间体提供了一条新途径。