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Outcomes for Female Physicians Compared With Nonphysicians After Assisted Reproductive Technology.
Obstetrics and Gynecology ( IF 5.7 ) Pub Date : 2024-10-24 , DOI: 10.1097/aog.0000000000005767 Anna C Vanderhoff,Andrea Lanes,Rachel Herz-Roiphe,Keizra Mecklai,Oscar Leyva Camacho,Serene S Srouji,Sarah Rae Easter,Janis Fox,Erika L Rangel
Obstetrics and Gynecology ( IF 5.7 ) Pub Date : 2024-10-24 , DOI: 10.1097/aog.0000000000005767 Anna C Vanderhoff,Andrea Lanes,Rachel Herz-Roiphe,Keizra Mecklai,Oscar Leyva Camacho,Serene S Srouji,Sarah Rae Easter,Janis Fox,Erika L Rangel
OBJECTIVE
To evaluate outcomes of female physicians after assisted reproductive technology (ART).
METHODS
We conducted a retrospective cohort study using data from 248 physician patients and 3,470 nonphysician patients who underwent a total of 10,095 fresh or frozen ART cycles at a single academic center in an insurance-mandated state between January 2015 and March 2022. The primary outcome was live-birth rate. The secondary outcomes were implantation rate, early pregnancy loss rate, and time to pregnancy. Models were adjusted for confounders where appropriate.
RESULTS
Both groups were similar in age (mean physician age 36.29 years; mean nonphysician age 35.96 years, P=.35). Physicians had lower body mass index (BMI) (mean physician BMI 23.51, mean nonphysician BMI 26.37, P<.01), and a higher proportion were diagnosed with unexplained infertility (physician 33.9%, nonphysician 25.9%, P<.01) and used preimplantation genetic testing for aneuploidy (physician 21.5%, nonphysician 12.7%). Physicians and nonphysicians had similar live-birth rates (physician 39.3%, nonphysician 38.2%; adjusted relative risk [aRR] 1.01 95% CI, 0.91-1.13), implantation rates (physician 34.7%, nonphysician 33.7%; relative risk 1.03 95% CI, 0.94-1.14), and early pregnancy loss rates (physician 21.9%, nonphysician 19.8%; aRR 1.18 95% CI, 0.99-1.41) per transfer. Physicians had a shorter time from initial ART cycle to pregnancy (physician 21.82 weeks, nonphysician 25.16 weeks; aRR 0.86, 95% CI, 0.83-0.89).
CONCLUSION
There was no difference between female physicians and nonphysicians in assisted reproduction cycle outcomes. Physicians become pregnant slightly faster than nonphysicians.
中文翻译:
辅助生殖技术后女医生与非医生相比的结果。
目的 评价女医生在辅助生殖技术 (ART) 后的结果。方法 我们使用 248 名医生患者和 3,470 名非医生患者的数据进行了一项回顾性队列研究,这些患者在 2015 年 1 月至 2022 年 3 月期间在保险强制州的单个学术中心接受了总共 10,095 个新鲜或冷冻的 ART 周期。主要结局是活产率。次要结局是植入率、早期妊娠丢失率和妊娠时间。在适当的情况下,针对混杂因素调整模型。结果 两组年龄相似 (医生平均年龄 36.29 岁;非医生平均年龄 35.96 岁,P=.35)。医生的体重指数 (BMI) 较低 (平均医生 BMI 23.51,平均非医生 BMI 26.37,P<.01),被诊断患有不明原因不孕症的比例较高 (医生 33.9%,非医生 25.9%,P<.01) 和使用植入前基因检测治疗非整倍体 (医生 21.5%,非医生 12.7%)。医生和非医生的活产率相似(医生 39.3%,非医生 38.2%;调整相对风险 [aRR] 1.01 95% CI,0.91-1.13),植入率 (医生 34.7%,非医生 33.7%;相对风险 1.03 95% CI,0.94-1.14)和早期妊娠丢失率 (医生 21.9%,非医生 19.8%;aRR 1.18 95% CI,0.99-1.41)。医生从初始 ART 周期到怀孕的时间更短(医生 21.82 周,非医生 25.16 周;aRR 0.86,95% CI,0.83-0.89)。结论 女医生和非医生在辅助生殖周期结局方面没有差异。医生怀孕的速度略快于非医生。
更新日期:2024-10-24
中文翻译:
辅助生殖技术后女医生与非医生相比的结果。
目的 评价女医生在辅助生殖技术 (ART) 后的结果。方法 我们使用 248 名医生患者和 3,470 名非医生患者的数据进行了一项回顾性队列研究,这些患者在 2015 年 1 月至 2022 年 3 月期间在保险强制州的单个学术中心接受了总共 10,095 个新鲜或冷冻的 ART 周期。主要结局是活产率。次要结局是植入率、早期妊娠丢失率和妊娠时间。在适当的情况下,针对混杂因素调整模型。结果 两组年龄相似 (医生平均年龄 36.29 岁;非医生平均年龄 35.96 岁,P=.35)。医生的体重指数 (BMI) 较低 (平均医生 BMI 23.51,平均非医生 BMI 26.37,P<.01),被诊断患有不明原因不孕症的比例较高 (医生 33.9%,非医生 25.9%,P<.01) 和使用植入前基因检测治疗非整倍体 (医生 21.5%,非医生 12.7%)。医生和非医生的活产率相似(医生 39.3%,非医生 38.2%;调整相对风险 [aRR] 1.01 95% CI,0.91-1.13),植入率 (医生 34.7%,非医生 33.7%;相对风险 1.03 95% CI,0.94-1.14)和早期妊娠丢失率 (医生 21.9%,非医生 19.8%;aRR 1.18 95% CI,0.99-1.41)。医生从初始 ART 周期到怀孕的时间更短(医生 21.82 周,非医生 25.16 周;aRR 0.86,95% CI,0.83-0.89)。结论 女医生和非医生在辅助生殖周期结局方面没有差异。医生怀孕的速度略快于非医生。