OBJECTIVE This study aimed to investigate the efficacy of two internet-delivered psychological treatments for hypoactive sexual desire dysfunction (HSDD) in women: internet-based cognitive behavioral sex therapy (iCBST) and internet-based mindfulness-based sex therapy (iMBST). METHOD Women with HSDD were randomly assigned to one of three groups: iCBST, iMBST, or a waitlist control group. The interventions consisted of eight modules delivered via an e-health platform with e-coach support to enhance adherence. Sexual desire and sexual distress were assessed at baseline and at 3-, 6-, and 12-month follow-ups (active conditions only). Per protocol, of the 266 consenting women, 106 were randomized to iCBST (Mage = 36.1, SD = 10.3), 106 to iMBST (Mage = 36.4, SD = 0.2), and 54 to the control condition (Mage = 36.7, SD = 11.0). Primary analyses utilized an intention-to-treat approach with linear mixed models. Clinical significance, assessed with clinical cutoffs and the reliable change index, was examined for active conditions. RESULTS Compared to the control condition, both iCBST and iMBST demonstrated significant improvements in sexual desire and sexual distress at 3-month (d = 0.89-1.14) and 6-month follow-up (d = 0.74-1.18). Results were sustained at 12-month follow-up, with 35 and 41% demonstrating reliable improvements and additional 20 and 24% achieving clinically significant improvements in sexual desire after iCBST and iMBST. Regarding sexual distress, 49 and 42% exhibited reliable change, with an additional 37%-42% achieving clinically significant improvements. CONCLUSIONS Results provide support for the overall long-term efficacy of psychological therapies in treating HSDD in women. However, fewer than one in four women showed improvements in sexual desire that met the threshold for clinically significant change. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

中文翻译：

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在线认知行为性疗法和在线正念性疗法治疗女性功能减退症的随机候补名单对照试验的结果。


目的 本研究旨在调查两种互联网提供的心理治疗对女性功能减退功能障碍 （HSDD） 的疗效：基于互联网的认知行为性疗法 （iCBST） 和基于互联网的正念性疗法 （iMBST）。方法 将 HSDD 女性随机分配到三组之一： iCBST 、 iMBST 或候补名单对照组。干预措施包括八个模块，通过电子健康平台提供，并提供电子教练支持，以提高依从性。在基线和 3 、 6 和 12 个月的随访中评估和性困扰 （仅限活动性疾病）。根据方案，在 266 名同意的女性中，106 名被随机分配到 iCBST（Mage = 36.1，SD = 10.3），106 名被随机分配到 iMBST（Mage = 36.4，SD = 0.2），54 名被随机分配到对照条件（Mage = 36.7，SD = 11.0）。初步分析采用线性混合模型的意向性治疗方法。使用临床临界值和可靠变化指数评估临床意义，检查活动性疾病。结果 与对照组相比，iCBST 和 iMBST 在 3 个月 （d = 0.89-1.14） 和 6 个月随访 （d = 0.74-1.18） 时均表现出和性困扰的显着改善。结果在 12 个月的随访中持续存在，35% 和 41% 的患者表现出可靠的改善，另外 20% 和 24% 的患者在 iCBST 和 iMBST 后实现了的临床显着改善。在性困扰方面，49% 和 42% 的患者表现出可靠的变化，另有 37%-42% 的患者实现了临床上显着的改善。结论 结果为心理疗法治疗女性 HSDD 的总体长期疗效提供了支持。 然而，只有不到四分之一的女性表现出改善，达到临床显着变化的阈值。（PsycInfo 数据库记录 （c） 2024 APA，保留所有权利）。