The picture for the long-term prediction of schizotypic individual difference features in relation to schizotypy assessed earlier in life remains opaque. Whereas schizotypy assessed earlier in life, typically during the late teen years, has been shown to predict nonaffective psychotic illness as well as the presence of nonaffective psychotic features (Chapman et al., 1994; Lenzenweger, 2021), the presence in midlife (mid-30s) of nonpsychotic schizotypic features in those assessed for schizotypy earlier in life remains to be demonstrated. The current study, which reports on a 17-year follow-up study, addresses this void in the schizotypy literature. Seventeen years after an initial psychometric assessment for schizotypy, in a sample of emerging adults (age = 18) with no prior history of psychotic illness, Perceptual Aberration Scale scores predicted elevated schizotypal personality features, increased schizophrenia-related personality disorder features (particularly schizotypal and paranoid), and elevated schizophrenia proneness scores at age 35. This pattern of associations was maintained even after the removal of participants with a diagnosis of nonaffective psychosis. The associations also remained largely unchanged net of state anxiety levels at initial and later assessments. These results support the emergence or maintenance of schizotypic psychopathology features consistent with a model that views schizotypy as the underlying liability for schizotypic psychopathology phenotypes. The results also provide additional support for both the construct validity of the initial psychometric schizotypy measure (Perceptual Aberration Scale) as well as the validity of the psychometric high-risk paradigm. Longitudinal research remains an illuminating and informative approach to understanding the nature of schizophrenia-related psychopathology by utilizing time as an essential scientific lever. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

中文翻译：

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分裂型 17 年后：预测中年分裂型个体差异。


与生命早期评估的分裂型个体差异特征相关的分裂型个体差异特征的长期预测图仍然不透明。而在生命早期，通常在青少年晚期评估的分裂型已被证明可以预测非情感性精神病以及非情感性精神病特征的存在（Chapman 等人，1994 年;Lenzenweger，2021 年），在中年（30 多岁）中，在生命早期接受精神分裂评估的人中存在非精神病性分裂型特征仍有待证明。目前的研究报告了一项为期 17 年的随访研究，解决了分裂型文献中的这一空白。在对分裂型进行初步心理测量评估 17 年后，在无精神病病史的新兴成年人（年龄 = 18 岁）样本中，知觉畸变量表评分预测了 35 岁时分裂型人格特征升高、精神分裂症相关人格障碍特征增加（尤其是分裂型和偏执型）和精神分裂症倾向评分升高。即使在去除被诊断为非情感性精神病的参与者后，这种关联模式也得以维持。在初始和后续评估中，扣除状态焦虑水平后，这些关联也基本保持不变。这些结果支持分裂型精神病理学特征的出现或维持，这与将分裂型视为分裂型精神病理学表型的潜在责任的模型一致。结果还为初始心理测量分裂型测量 （知觉像差量表） 的结构效度以及心理测量高风险范式的有效性提供了额外的支持。 纵向研究仍然是一种具有启发性和信息量的方法，通过利用时间作为重要的科学杠杆来理解精神分裂症相关精神病理学的性质。（PsycInfo 数据库记录 （c） 2024 APA，保留所有权利）。