Antisocial behavior (ASB) refers to a set of behaviors that violate social norms and disregard the well-being and rights of others. In this review, we synthesize evidence from studies using genetically informed designs to investigate the genetic and environmental contributions to individual differences in ASB. We review evidence from studies using family data (twin and adoption studies) and measured DNA (candidate gene and genome-wide association studies) that have informed our understanding of ASB. We describe how genetically informative designs are especially suited to investigate the nature of environmental risk and the forms of gene–environment interplay. We also highlight clinical and legal implications, including how insights from genetically informed research can help inform prevention and intervention, and we discuss some challenges and opportunities within this field of research.

中文翻译：

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通过基因研究揭示反社会行为


反社会行为 （ASB） 是指一系列违反社会规范并无视他人福祉和权利的行为。在本综述中，我们综合了使用遗传知情设计的研究证据，以调查遗传和环境对 ASB 个体差异的贡献。我们回顾了使用家庭数据 （双胞胎和收养研究） 和测量 DNA （候选基因和全基因组关联研究） 的研究证据，这些研究为我们对 ASB 的理解提供了信息。我们描述了遗传信息设计如何特别适合研究环境风险的性质和基因-环境相互作用的形式。我们还强调了临床和法律影响，包括来自遗传学研究的见解如何帮助为预防和干预提供信息，并讨论了该研究领域的一些挑战和机遇。