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Micronutrients and Androgenetic Alopecia: A Systematic Review
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-10-23 , DOI: 10.1002/mnfr.202400652 Ruilong Wang, Jinran Lin, Qingmei Liu, Wenyu Wu, Jinfeng Wu, Xiao Liu
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-10-23 , DOI: 10.1002/mnfr.202400652 Ruilong Wang, Jinran Lin, Qingmei Liu, Wenyu Wu, Jinfeng Wu, Xiao Liu
ScopeHair loss is a common problem that can negatively impact individuals' psychological well‐being. Androgenetic alopecia (AGA) is one of the most prevalent types of nonscarring hair loss. This review summarizes the existing evidence on the relationship between AGA and various micronutrients, including vitamin B, vitamin D, vitamin A, vitamin C, iron, selenium, zinc, manganese, and copper.MethodsA literature search was conducted to identify relevant articles published between 1993 and 2023. The search identified 49 relevant articles.ResultsThe findings suggest that deficiencies or imbalances in these micronutrients may contribute to the pathogenesis of AGA and represent modifiable risk factors for hair loss prevention and treatment. Vitamin B, vitamin D, iron, and zinc appear to play critical roles in hair growth and maintenance. Deficiencies in these micronutrients have been associated with increased risk of AGA, while supplementation with these nutrients has shown potential benefits in improving hair growth and preventing hair loss. However, the current evidence is not entirely consistent, with some studies reporting no significant associations.ConclusionDeficiencies or imbalances in specific vitamins and minerals, especially vitamin B, vitamin D, Fe, Se, and Zn are involved in the pathogenesis of AGA and may represent modifiable risk factors for the treatment and prevention of this condition.
中文翻译:
微量营养素和雄激素性脱发:系统评价
范围脱发是一个常见的问题,会对个人的心理健康产生负面影响。雄激素性脱发 (AGA) 是最普遍的非疤痕性脱发类型之一。本综述总结了 AGA 与各种微量营养素之间关系的现有证据,包括维生素 B、维生素 D、维生素 A、维生素 C、铁、硒、锌、锰和铜。方法进行文献检索以确定 1993 年至 2023 年间发表的相关文章。检索确定了 49 篇相关文章。结果研究结果表明,这些微量营养素的缺乏或不平衡可能导致 AGA 的发病机制,并代表脱发预防和治疗的可改变风险因素。维生素 B、维生素 D、铁和锌似乎在头发生长和维持中起着关键作用。这些微量营养素的缺乏与 AGA 风险增加有关,而补充这些营养素在改善头发生长和防止脱发方面显示出潜在益处。然而,目前的证据并不完全一致,一些研究报告没有显著的关联。结论特定维生素和矿物质,尤其是维生素 B、维生素 D、Fe、Se 和 Zn 的缺乏或不平衡与 AGA 的发病机制有关,可能是治疗和预防该病的可改变危险因素。
更新日期:2024-10-23
中文翻译:
微量营养素和雄激素性脱发:系统评价
范围脱发是一个常见的问题,会对个人的心理健康产生负面影响。雄激素性脱发 (AGA) 是最普遍的非疤痕性脱发类型之一。本综述总结了 AGA 与各种微量营养素之间关系的现有证据,包括维生素 B、维生素 D、维生素 A、维生素 C、铁、硒、锌、锰和铜。方法进行文献检索以确定 1993 年至 2023 年间发表的相关文章。检索确定了 49 篇相关文章。结果研究结果表明,这些微量营养素的缺乏或不平衡可能导致 AGA 的发病机制,并代表脱发预防和治疗的可改变风险因素。维生素 B、维生素 D、铁和锌似乎在头发生长和维持中起着关键作用。这些微量营养素的缺乏与 AGA 风险增加有关,而补充这些营养素在改善头发生长和防止脱发方面显示出潜在益处。然而,目前的证据并不完全一致,一些研究报告没有显著的关联。结论特定维生素和矿物质,尤其是维生素 B、维生素 D、Fe、Se 和 Zn 的缺乏或不平衡与 AGA 的发病机制有关,可能是治疗和预防该病的可改变危险因素。