PURPOSE OF REVIEW To explore and summarize recent work examining the use of platelet-rich plasma (PRP) applications for vocal fold disorder. RECENT FINDINGS Intrachordal PRP injections have recently emerged as a treatment option for patients with damage to the lamina propria of the vocal fold (scar, atrophy, sulcus and inflammatory lesions). Studies support significant improvements in patient-reported and clinician-reported outcomes, and objective phonatory parameters. PRP demonstrates a good safety profile, absence of immune reactions, affordable cost model and improvement in mucosal wave features with resultant improved voice quality up to 12 months following treatment. SUMMARY PRP injection of the vocal folds is a novel repurposing of a previously validated technique, and emerging data shows consistent results across multiple centres, increasing confidence in use of this freely available material. Current published studies confirm improved voice outcomes compared with pretreatment measures and high patient satisfaction. Further research is required to properly assign the role of and ideal candidate for PRP applications, and to delineate durability of treatment.

中文翻译：

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富含血小板的血浆在喉部的应用：蛇油还是惊人的？


评价目的 探讨和总结最近研究富血小板血浆 （PRP） 在声带障碍中的应用的工作。最近的发现 脊索内 PRP 注射最近已成为声带固有层损伤（疤痕、萎缩、沟和炎症病变）患者的一种治疗选择。研究支持患者报告和临床医生报告的结果以及客观发音参数的显著改善。PRP 具有良好的安全性、无免疫反应、负担得起的成本模型和粘膜波特征的改善，从而在治疗后长达 12 个月内改善了语音质量。摘要 声带的 PRP 注射是对先前验证的技术的一种新颖的再利用，新出现的数据显示多个中心的结果一致，增加了使用这种免费材料的信心。目前发表的研究证实，与治疗前措施相比，语音结果得到改善，患者满意度高。需要进一步的研究来正确分配 PRP 应用的作用和理想候选者，并描述治疗的持久性。