Persons with end-stage kidney disease treated with dialysis experience distressing reductions in quality of life and increased mortality. Few large, randomized trials in nephrology have reported on health-related quality of life. Rose et al. report beneficial effects of high-volume hemodiafiltration versus high-flux hemodialysis on secondary end points of health-related quality of life in the CONVINCE trial (Comparison of High Dose Hemodiafiltration with High Flux Hemodialysis Trial). These results raise questions regarding hemodiafiltration as a potential modality to preserve health-related quality of life in end-stage kidney disease.

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透析方式和生活质量：更多答案，更多问题。


接受透析治疗的终末期肾病患者生活质量下降和死亡率增加令人痛苦。很少有肾脏病学的大型随机试验报告与健康相关的生活质量。Rose 等人在 CONVINCE 试验（高剂量血液透析滤过与高通量血液透析试验的比较）中报告了高容量血液透析滤过与高通量血液透析相比对健康相关生活质量次要终点的有益影响。这些结果提出了关于血液透析滤过作为保持终末期肾病健康相关生活质量的潜在方式的问题。