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Patients with crush syndrome and kidney disease: lessons learned from the earthquake in Kahramanmaraş, Türkiye.
Kidney International ( IF 14.8 ) Pub Date : 2024-11-01 , DOI: 10.1016/j.kint.2024.08.008 Savas Ozturk,Serhan Tuglular,Refik Olmaz,Ismail Kocyigit,Muge Uzerk Kibar,Kenan Turgutalp,Dilek Torun,Tuncay Sahutoglu,Ozlem Usalan,Ozkan Gungor,Ramazan Danis,Gursel Yildiz,Ali Gurel,Mehmet Horoz,Mehmet Kucuksu,Suleyman Karakose,Tolga Yildirim,Mehmet Riza Altiparmak,Mehmet Deniz Ayli,Murat Tugcu,Zehra Eren,Eray Eroglu,Yasemin Coskun Yavuz,Esra Akcali,Dede Sit,Mehmet Polat,Saliha Yildirim,Selma Alagoz,Sibel Gokcay Bek,Irem Pembegul,Tahsin Karaaslan,Mustafa Keles,Funda Sari,Ayca Inci,Numan Gorgulu,Gulizar Sahin,Zeki Aydin,Serap Yadigar,Ozkan Ulutas,Nedim Yilmaz Selcuk,Yavuz Ayar,Zeynep Bal,Murat Altunok,Ayse Jini Günes Keskin,Murat Hayri Sipahioglu,Meliha Ozkutlu,Belda Dursun,Aysegul Oruc,Nuri Baris Hasbal,Mustafa Sevinc,Semih Gul,Seda Safak Ozturk,Alaattin Yildiz,Mehmet Sukru Sever
Kidney International ( IF 14.8 ) Pub Date : 2024-11-01 , DOI: 10.1016/j.kint.2024.08.008 Savas Ozturk,Serhan Tuglular,Refik Olmaz,Ismail Kocyigit,Muge Uzerk Kibar,Kenan Turgutalp,Dilek Torun,Tuncay Sahutoglu,Ozlem Usalan,Ozkan Gungor,Ramazan Danis,Gursel Yildiz,Ali Gurel,Mehmet Horoz,Mehmet Kucuksu,Suleyman Karakose,Tolga Yildirim,Mehmet Riza Altiparmak,Mehmet Deniz Ayli,Murat Tugcu,Zehra Eren,Eray Eroglu,Yasemin Coskun Yavuz,Esra Akcali,Dede Sit,Mehmet Polat,Saliha Yildirim,Selma Alagoz,Sibel Gokcay Bek,Irem Pembegul,Tahsin Karaaslan,Mustafa Keles,Funda Sari,Ayca Inci,Numan Gorgulu,Gulizar Sahin,Zeki Aydin,Serap Yadigar,Ozkan Ulutas,Nedim Yilmaz Selcuk,Yavuz Ayar,Zeynep Bal,Murat Altunok,Ayse Jini Günes Keskin,Murat Hayri Sipahioglu,Meliha Ozkutlu,Belda Dursun,Aysegul Oruc,Nuri Baris Hasbal,Mustafa Sevinc,Semih Gul,Seda Safak Ozturk,Alaattin Yildiz,Mehmet Sukru Sever
This study investigated in-hospital outcomes and related factors in patients diagnosed with postearthquake crush syndrome after the earthquakes in Kahramanmaraş, Türkiye. One thousand twenty-four adult patients diagnosed with crush syndrome were analyzed. Data on demographic characteristics, clinical presentation, laboratory values, treatments, and outcomes were collected. A total of 9.8% of patients died during their hospital stay. Nonsurvivors were generally older, more likely to have preexisting chronic kidney disease, and faced more severe injuries and complications, including hypotension-shock, arrhythmias, elevated markers of renal dysfunction, and higher rates of acute kidney injury (AKI) and compartment syndrome. In addition, intensive care unit needs were higher. Multivariate analysis confirmed that age, injury severity, shock, high potassium, uric acid, and lactate levels on admission, development of AKI, compartment syndrome, and intensive care unit admission were significant predictors of mortality. Better disaster preparedness and improved health care infrastructure could be potential explanations for improved in-hospital mortality in the current era, as compared to previous earthquakes.
中文翻译:
挤压综合征和肾病患者:从土耳其 Kahramanmaraş 地震中吸取的教训。
本研究调查了土耳其 Kahramanmaraş 地震后被诊断患有震后挤压综合征的患者的院内结果和相关因素。分析了 124 名被诊断患有挤压综合征的成年患者。收集了有关人口学特征、临床表现、实验室值、治疗和结局的数据。共有 9.8% 的患者在住院期间死亡。非幸存者通常年龄较大,更有可能患有既往慢性肾病,并面临更严重的伤害和并发症,包括低血压休克、心律失常、肾功能不全标志物升高以及急性肾损伤 (AKI) 和骨筋膜室综合征的发生率较高。此外,重症监护病房的需求更高。多变量分析证实,年龄、损伤严重程度、休克、入院时高钾、尿酸和乳酸水平、AKI 的发展、隔室综合征和重症监护病房收治是死亡率的重要预测因素。与以前的地震相比,更好的备灾和改善的医疗保健基础设施可能是当前时代院内死亡率降低的潜在解释。
更新日期:2024-10-23
中文翻译:
挤压综合征和肾病患者:从土耳其 Kahramanmaraş 地震中吸取的教训。
本研究调查了土耳其 Kahramanmaraş 地震后被诊断患有震后挤压综合征的患者的院内结果和相关因素。分析了 124 名被诊断患有挤压综合征的成年患者。收集了有关人口学特征、临床表现、实验室值、治疗和结局的数据。共有 9.8% 的患者在住院期间死亡。非幸存者通常年龄较大,更有可能患有既往慢性肾病,并面临更严重的伤害和并发症,包括低血压休克、心律失常、肾功能不全标志物升高以及急性肾损伤 (AKI) 和骨筋膜室综合征的发生率较高。此外,重症监护病房的需求更高。多变量分析证实,年龄、损伤严重程度、休克、入院时高钾、尿酸和乳酸水平、AKI 的发展、隔室综合征和重症监护病房收治是死亡率的重要预测因素。与以前的地震相比,更好的备灾和改善的医疗保健基础设施可能是当前时代院内死亡率降低的潜在解释。