Microfluidic systems incorporating magnetic droplets have emerged as a focal point of significant interest within the biomedical domain. The allure of these systems lies in their capacity to offer precise control, enable contactless operation, and accommodate minimal sample concentration requirements. Such remarkable features serve to mitigate errors arising from human operation and other factors during cell or molecular detection. By providing innovative solutions for molecular diagnostics and immunoassay applications, magnetic droplet microfluidics enhance the accuracy and efficiency of these procedures. This review undertakes a comprehensive examination of the research progress in microfluidic systems centered around magnetic droplets. It adheres to a sequential presentation approach, commencing from the fundamental operation principles, specifically the generation of magnetic droplets on the microfluidic chip, and proceeding to their transmission and mixing within the microchannel via an array of operating techniques. Additionally, the relevant detection technologies associated with magnetic drop microfluidics and their numerous applications within the biomedical field are systematically classified and reviewed. The overarching objective of this review is to spotlight key advancements and offer valuable insights into the future trajectory of this burgeoning field.

中文翻译：

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微流控芯片中磁滴的产生、操作、检测和生物医学应用


包含磁滴的微流体系统已成为生物医学领域备受关注的焦点。这些系统的魅力在于它们能够提供精确控制，实现非接触式操作，并满足最低的样品浓度要求。这些显著的特点有助于减少细胞或分子检测过程中因人为操作和其他因素而产生的误差。通过为分子诊断和免疫分析应用提供创新解决方案，磁滴微流体技术提高了这些程序的准确性和效率。本文对以磁滴为中心的微流控系统的研究进展进行了全面考察。它坚持顺序呈现方法，从基本操作原理开始，特别是在微流体芯片上产生磁滴，然后通过一系列操作技术在微通道内传输和混合磁滴。此外，还系统地对与磁滴微流控相关的检测技术及其在生物医学领域的众多应用进行了系统分类和回顾。本综述的总体目标是突出关键进展，并为这一新兴领域的未来发展轨迹提供有价值的见解。