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Invasive Group A Streptococcus Hypervirulent M1UK Clone, Canada, 2018–2023
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2024-10-20 , DOI: 10.3201/eid3011.241068 Alyssa R. Golden, Averil Griffith, Gregory J. Tyrrell, Julianne V. Kus, Allison McGeer, Marc-Christian Domingo, Jennifer Grant, Jessica Minion, Paul Van Caeseele, Guillaume Desnoyers, David Haldane, Yang Yu, Xiaofeng Ding, Laura Steven, Jan McFadzen, Courtney Primeau, Irene Martin
中文翻译：
侵袭性 A 组高毒力链球菌 M1UK 克隆，加拿大，2018-2023 年
更新日期：2024-10-21
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2024-10-20 , DOI: 10.3201/eid3011.241068 Alyssa R. Golden, Averil Griffith, Gregory J. Tyrrell, Julianne V. Kus, Allison McGeer, Marc-Christian Domingo, Jennifer Grant, Jessica Minion, Paul Van Caeseele, Guillaume Desnoyers, David Haldane, Yang Yu, Xiaofeng Ding, Laura Steven, Jan McFadzen, Courtney Primeau, Irene Martin
To determine invasive group A Streptococcus trends in Canada, we characterized emm1 isolates collected during 2018–2023. The percentage of hypervirulent M1UK lineage isolates increased significantly, from 22.1% in 2018 to 60.2% in 2023. Genomic analysis identified geographically and temporally associated clusters and genes associated with virulent bacteriophage acquisition.
中文翻译：
侵袭性 A 组高毒力链球菌 M1UK 克隆，加拿大，2018-2023 年
为了确定加拿大侵袭性 A 组链球菌的趋势，我们对 2018-2023 年期间收集的 emm1 分离株进行了表征。高毒力 M1UK 谱系分离株的百分比显着增加，从 2018 年的 22.1% 增加到 2023 年的 60.2%。基因组分析确定了与毒力噬菌体获得相关的地理和时间相关的簇和基因。
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