ImportanceThere is a need to improve the evidence base for gender-affirming medical care provided to adolescents, including the experiences of those who have received this care.ObjectiveTo examine rates of satisfaction, regret, and continuity of care in adolescents who received puberty blockers and/or gender-affirming hormones as part of gender-affirming medical care.Design, Setting, and ParticipantsThis survey study used the 2023 online survey wave of an ongoing longitudinal study, the Trans Youth Project, among a community-based sample of transgender youth and their parents initially recruited throughout the US and Canada between 2013 and 2017. The satisfaction and regret data include responses from a youth or their parent representing 87% of the youth aged 12 years or older in the cohort who have received gender-affirming medical care (235 of 269 youths). Of these, 220 completed the 2023 survey (main sample); information about continuity of care was available for all youth. Data analysis was performed from April to August 2024.ExposureSatisfaction, regret, and continuity of care following puberty blockers or suppression and/or gender-affirming hormones.Main Outcomes and MeasuresSelf- or parent-reported satisfaction or regret with gender-affirming care and continuation of care.ResultsAmong the 220 youths in the main sample (mean [SD] age, 16.07 [2.40] years; 30 [14%] multiracial, non-Hispanic; 18 [8%] White, Hispanic; 155 [70%] White, non-Hispanic; 17 [8%] other race and ethnicity, including Asian, Black [Hispanic and non-Hispanic], Hispanic with unknown race, multiracial Hispanic, or Native American; gender at last interaction: 68 [31%] boys, 132 [60%] girls, 20 [9%] gender diverse, eg, nonbinary) and their parents, very high levels of satisfaction and low levels of regret with puberty blockers and gender-affirming hormones as well as high levels of continuation of care were reported. Of these 220 respondents in the main sample, 9 were regretful of having received blockers (n = 8) and/or hormones (n = 3; 2 of these individuals reported regret with both), of whom 4 have stopped all gender-affirming medical care and 1 has continued to receive blockers but plans to stop. The 4 others have continued care, suggesting that regret is not synonymous with stopping care.Conclusions and RelevanceThe findings suggest that youth accessing puberty blockers and hormones as part of gender-affirming care tend to be satisfied with and not regretful of that care several years later. While regret was rare, these experiences need to be better understood.

中文翻译：

---

青春期对性别肯定医疗的满意度和遗憾程度


重要性有必要改善向青少年提供性别肯定医疗保健的证据基础，包括接受这种护理的人的经历。目的检查接受青春期阻断剂和/或性别肯定激素作为性别肯定医疗护理一部分的青少年的满意度、遗憾率和护理连续性。设计、设置和参与者这项调查研究使用了一项正在进行的纵向研究“跨性别青年项目”的 2023 年在线调查浪潮，该调查在 2013 年至 2017 年期间最初在美国和加拿大招募的跨性别青年及其父母的社区样本中进行。满意度和遗憾数据包括来自青少年或其父母的回答，占队列中 87% 的 12 岁或以上接受性别肯定医疗保健的青少年（269 名青少年中的 235 名）。其中，220 人完成了 2023 年的调查（主要样本）;所有青少年都可以获得有关护理连续性的信息。数据分析于 2024 年 4 月至 8 月进行。暴露青春期阻断剂或抑制和/或性别肯定激素后护理的满意度、遗憾和连续性。主要结局和措施自我或父母报告对性别肯定护理和持续护理的满意度或遗憾。结果在主样本的 220 名青少年中（平均 [SD] 年龄，16.07 [2.40] 年;30 [14%] 多种族、非西班牙裔;18 [8%] 白人，西班牙裔;155 [70%] 白人，非西班牙裔;17 [8%] 其他种族和族裔，包括亚洲人、黑人 [西班牙裔和非西班牙裔]、种族未知的西班牙裔、多种族西班牙裔或美洲原住民;最后一次互动时的性别：68 [31%] 男孩，132 [60%] 女孩，20 [9%] 性别多样化，例如非二元性别）和他们的父母，对青春期阻断剂和性别肯定激素的满意度非常高，后悔程度低，以及高水平的持续护理被报告。在主样本的这 220 名受访者中，9 人后悔接受了阻滞剂 （n = 8） 和/或激素 （n = 3;其中 2 人报告对两者感到后悔），其中 4 人已停止所有性别肯定的医疗保健，1 人继续接受阻滞剂但计划停止。其他 4 人继续接受护理，这表明后悔并不等同于停止护理。结论和相关性研究结果表明，作为性别肯定护理的一部分，获得青春期阻断剂和激素的青少年往往在几年后对这种护理感到满意并且不后悔。虽然遗憾很少见，但这些经历需要更好地理解。