Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2024-10-19 , DOI: 10.3201/eid3011.240329 Sarah Gorvetzian, Antonio G. Pacheco, Erin Anderson, Susan M. Ray, Marcos C. Schechter
Limited data exist on mortality rates after tuberculosis (TB) treatment in the United States. We analyzed mortality rates for all adults in Georgia, USA, who had a TB diagnosis and finished treatment during January 1, 2008–December 31, 2019. We obtained posttreatment mortality rate data from the National Death Index and calculated standardized mortality ratios (SMRs) for TB treatment survivors and the general Georgia population. Among 3,182 TB treatment survivors, 233 (7.3%) had died as of December 31, 2019. The overall TB cohort age- and sex-adjusted SMR was 0.89 (95% CI 0.73–1.05). The SMR among US-born TB treatment survivors was 1.56 (95% CI 1.36–1.77). In the TB cohort, US-born status, HIV co-infection, excess alcohol use, diabetes mellitus, and end-stage renal disease were associated with increased risk for death after TB treatment. TB treatment survivors could benefit from improved linkage to primary and HIV comprehensive care to prevent posttreatment death.
中文翻译:
结核病治疗后的死亡率,美国佐治亚州,2008-2019 年
美国结核病 (TB) 治疗后死亡率的数据有限。我们分析了 2008 年 1 月 1 日至 2019 年 12 月 31 日期间美国佐治亚州所有被诊断为结核病并完成治疗的成年人的死亡率。我们从国家死亡指数获得了治疗后死亡率数据,并计算了结核病治疗幸存者和佐治亚州一般人群的标准化死亡率 (SMR)。截至 2019 年 12 月 31 日,在 3,182 名结核病治疗幸存者中,有 233 人 (7.3%) 死亡。总体 TB 队列年龄和性别校正 SMR 为 0.89 (95% CI 0.73–1.05)。美国出生的结核病治疗幸存者的 SMR 为 1.56 (95% CI 1.36-1.77)。在 TB 队列中,美国出生状态、HIV 合并感染、过量饮酒、糖尿病和终末期肾病与 TB 治疗后死亡风险增加相关。结核病治疗幸存者可以从改善与初级和 HIV 综合护理的联系中受益,以防止治疗后死亡。