The Kirschner wire (K-wire) is widely used in orthopedic external fixation due to its versatility and clinical effectiveness. However, a significant challenge associated with its use is the potential for bacterial migration, subsequent infection, and dislodgement as the wire penetrates the skin and bone. This study introduces a novel bioactive material, selenium/calcium silicate (Se/β-CS), achieved by integrating selenium—an essential trace element in the human body—into bioceramic calcium silicate. This integration was accomplished using a combined chemical co-deposition method and redox reaction. Furthermore, a uniform and controllable Se/β-CS coating was applied to the K-wire's surface using the Langmuir-Blodgett technique. This coating gradually releases active components—Si, Ca, and Se—that effectively eliminate bacterial infections and promote osteointegration. The findings of this study offer promising opportunities for the use of robust and multifunctional coating materials on implantable devices, particularly within the fields of orthopedics, transplantation, and surgery.

中文翻译：

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微量元素硒增强克氏线，具有增强的成骨和抗菌特性


克氏丝 （K-wire） 由于其多功能性和临床有效性而广泛用于骨科外固定术。然而，与其使用相关的一个重大挑战是当金属丝穿透皮肤和骨骼时，细菌迁移、后续感染和移位的可能性。本研究介绍了一种新型生物活性材料，即硒/硅酸钙 （Se/β-CS），它是通过将硒（人体必需的微量元素）整合到生物陶瓷硅酸钙中来实现的。这种整合是使用化学共沉积方法和氧化还原反应相结合的方式完成的。此外，使用 Langmuir-Blodgett 技术将均匀且可控的 Se/β-CS 涂层应用于 K-wire 的表面。这种涂层逐渐释放活性成分 Si、Ca 和 Se，有效消除细菌感染并促进骨整合。这项研究的结果为在植入式设备上使用坚固和多功能的涂层材料提供了有希望的机会，特别是在骨科、移植和外科领域。