Ovarian cancer remains resistant to immunotherapy in most patients, highlighting the need to make these tumors more immunogenic. A recent study unveils how chemotherapy is able to induce cancer cell stress in metastatic ovarian carcinomas, inducing the formation of tertiary lymphoid structures that create a “hotter” tumor microenvironment.

中文翻译：

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化疗在转移性卵巢癌中引发三级淋巴结构


大多数患者对免疫治疗仍然有抵抗力，这凸显了使这些肿瘤更具免疫原性的必要性。最近的一项研究揭示了化疗如何在转移性卵巢癌中诱导癌细胞应激，诱导形成三级淋巴结构，从而产生“更热”的肿瘤微环境。