In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999–2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002–2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.

中文翻译：

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百日咳杆菌素缺乏症百日咳博德特氏菌分离株的患病率，斯洛文尼亚

在斯洛文尼亚，1999 年至 2016 年期间主要使用含有 pertactin （PRN） 的原发性无细胞百日咳疫苗 （ACV）;没有 PRN 的 ACV 于 2017 年推出。在 2002-2020 年收集的 123 株百日咳博德特氏菌菌株中，共有 48 株是 PRN 缺陷型;44 例是在 2017 年之后收集的。ACV 的变化可能会增加 PRN 缺陷型百日咳杆菌和感染。