Data on COVID-19 cases, deaths, hospitalizations, and vaccinations in Oklahoma, USA, have not been systematically described. The relationship between vaccination and COVID-19–related outcomes over time has not been investigated. We graphically described data collected during February 2020–December 2021 and conducted spatiotemporal modeling of monthly increases in COVID-19 cumulative death and hospitalization rates, adjusting for cumulative case rate, to explore the relationship. A 1 percentage point increase (absolute change) in the cumulative vaccination rate was associated with a 6.3% (95% CI 1.4%–10.9%) relative decrease in death outcome during April–June 2021, and a 1.9% (95% CI 1.1%–2.6%) relative decrease in death outcome and 1.1% (95% CI 0.5%–1.7%) relative decrease in hospitalization outcome during July–December 2021; the effect on hospitalizations was driven largely by data from urban counties. Our findings from Oklahoma suggest that increasing cumulative vaccination rates might reduce the increase in cumulative death and hospitalization rates from COVID-19.

有关美国俄克拉荷马州 COVID-19 病例、死亡、住院和疫苗接种的数据尚未得到系统描述。疫苗接种与 COVID-19 相关结果随时间推移之间的关系尚未得到调查。我们以图形方式描述了 2020 年 2 月至 2021 年 12 月期间收集的数据，并对 COVID-19 累积死亡率和住院率的每月增加进行了时空建模，并根据累积病例率进行调整，以探索这种关系。累积疫苗接种率增加 1 个百分点（绝对变化）与 2021 年 4 月至 6 月期间死亡结果相对减少 6.3%（95% CI 1.4%-10.9%）相关，2021 年 7 月至 12 月期间死亡结果相对减少 1.9%（95% CI 1.1%-2.6%）和住院结果相对减少 1.1%（95% CI 0.5%-1.7%）;对住院人数的影响主要是由城市县的数据驱动的。我们在俄克拉荷马州的调查结果表明，提高累积疫苗接种率可能会减少 COVID-19 累积死亡率和住院率的增加。