Nature Food ( IF 23.6 ) Pub Date : 2024-10-18 , DOI: 10.1038/s43016-024-01061-3 Corbin M. Goodwin, William R. Aimutis, Rohan A. Shirwaiker
Techno-economic analyses offer insights into how industrial cultivated meat (CM) production could achieve price parity with conventional meat. These analyses use scaling practices, data and facility designs for related bioprocessing fields, including large (≥20,000 l) stirred tank bioreactors and suspension-tolerant, continuously available cell lines. This approach is inconsistent with most primary CM literature, which parallels bench-scale tissue engineering. TEAs published to date demonstrate that, under the current technological paradigm, CM is unlikely to be competitive with conventional meat. Scale-up feasibility may hinge on cost-saving areas such as use of plant-based media components, food-grade aseptic conditions and extensive scaling of related supply chains. Research must address knowledge gaps including serum-free differentiation, new bioreactor designs and facility design before CM can become a viable alternative to animal-based meat production.
中文翻译:
对培育肉技术经济分析的范围综述,为扩大生产的未来研究方向提供信息
技术经济分析为工业化培育肉 (CM) 生产如何实现与传统肉类的价格平价提供了见解。这些分析使用相关生物加工领域的放大实践、数据和设施设计,包括大型 (≥20,000 L) 搅拌罐式生物反应器和耐悬、连续可用的细胞系。这种方法与大多数初级 CM 文献不一致,后者与实验室规模的组织工程相似。迄今为止发布的 TEA 表明,在当前的技术范式下,CM 不太可能与传统肉类竞争。扩大规模的可行性可能取决于节省成本的领域,例如使用植物基培养基成分、食品级无菌条件以及相关供应链的广泛扩展。在 CM 成为动物肉生产的可行替代方案之前,研究必须解决知识差距,包括无血清分化、新的生物反应器设计和设施设计。