Genetic mutation carriers of frontotemporal dementia can remain cognitively well despite neurodegeneration. A better understanding of brain structural, perfusion, and functional patterns in the pre-symptomatic stage could inform accurate staging and potential mechanisms.

中文翻译：

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额顶网络完整性支持症状前额颞叶痴呆的认知功能：脑功能、结构和灌注的多模态分析


额颞叶痴呆的基因突变携带者尽管神经退化，但仍能保持良好的认知状态。更好地了解症状前阶段的大脑结构、灌注和功能模式可以为准确的分期和潜在机制提供信息。