Recently, Li’s group designed a conceptually novel radical strategy for site-selective functionalization of ultra-remote arene C–H bond. The arenes were activated by intramolecular nitrogen-centered radical instead of generally used C–H metalation. The NHC-catalyzed radical cross-coupling acts as the key step to forging C–C bond at the para position of the arenes.

中文翻译：

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NHC 催化的远程位点选择性芳烃 C-H 酰化


最近，Li 的小组设计了一种概念上新颖的自由基策略，用于超远程芳烃 C-H 键的位点选择性官能化。芳烃由分子内氮中心自由基激活，而不是通常使用的 C-H 金属化。NHC 催化的自由基交叉偶联是在芳烃的对位形成 C-C 键的关键步骤。