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A History of Polymyalgia Rheumatica: A Narrative Review
Rheumatology ( IF 4.7 ) Pub Date : 2024-10-16 , DOI: 10.1093/rheumatology/keae569
Shirley Shah, Sinchna Rao, Sarah L Mackie, Chetan B Mukhtyar

Polymyalgia rheumatica (PMR) is characterised by stiffness and pain in the shoulders, hips, and neck and presents most commonly in the eighth decade. It can coexist with giant cell arteritis and the two diseases may share some pathophysiological mechanisms. This narrative review considers present-day ideas about PMR in a historical context, from the first names and descriptions of this disease entity, via successive generations of classification criteria sets, and finally to implications for clinical diagnosis. The characteristic distribution of musculoskeletal inflammation in PMR, and its relationship to vasculitic and synovitic diseases, have framed the way that PMR is described, classified, diagnosed and treated. A response to glucocorticoids is not specific to PMR and so it is important for rheumatologists to support general practitioners in making a definite diagnosis. Multi-stakeholder collaboration will improve current pathways for fast, accurate diagnosis and safe and effective treatment.

中文翻译:


风湿性多肌痛的历史:叙述性回顾



风湿性多肌痛 (PMR) 的特征是肩部、臀部和颈部僵硬和疼痛,最常见于八十岁。它可以与巨细胞动脉炎共存,两种疾病可能具有一些共同的病理生理机制。本叙述性综述在历史背景下考虑了当今关于 PMR 的想法,从该疾病实体的名字和描述,到连续几代的分类标准集,最后到对临床诊断的影响。PMR 中肌肉骨骼炎症的特征性分布及其与血管炎和滑膜疾病的关系,构成了 PMR 的描述、分类、诊断和治疗方式。对糖皮质激素的反应并非 PMR 所特有的,因此风湿病学家支持全科医生做出明确诊断很重要。多方利益相关者合作将改善当前快速、准确诊断和安全有效治疗的途径。
更新日期:2024-10-16
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