Background We developed a high-intensity parenting intervention (HIP) to help parents support the academic success of childhood cancer survivors (CCSs), who often face post-treatment challenges affecting their school-related functioning. This randomized controlled trial (NCT03178617) evaluated HIP’s efficacy compared to lower-intensity, single-session, treatment-as-usual services (LIP) in Latino families. Primary outcomes were parenting efficacy and CCSs’ school functioning; secondary outcomes included parenting knowledge and measures of CCSs’ academic performance, attention, and functioning outside of school. Methods 106 Latino survivors of childhood leukemia and lymphoblastic lymphoma (aged 6–12 years) and their parents were randomly assigned to HIP (n = 54) or LIP (n = 52). Linear mixed-effects models evaluated group differences across baseline, 6-month (T2), and 12-month (T3) assessments. Results Parenting efficacy and knowledge improved significantly in the HIP arm, resulting in higher scores vs LIP at T2 and T3 (P ≤ .01). No significant between-group differences were found in child school functioning; however, HIP children showed significantly better social functioning and performance on one measure of attention (CPT-3 commissions) at T3 (P < .05). While HIP adherence challenges were observed, with only 33 (61%) completing the intervention, exploratory analyses suggest that benefits were most evident among those who fully engaged. Satisfaction and perceived benefit were greater for HIP vs LIP at both time points (P < .05). Conclusions Our results suggest the potential value of parent-directed behavioral interventions like HIP for CCSs and their families. Further studies are needed to address participation barriers and enhance engagement to maximize and sustain benefits.

中文翻译：

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减少拉丁裔癌症儿童的学习和社会心理差异：一项随机干预试验


背景 我们开发了一种高强度育儿干预 （HIP），以帮助父母支持儿童癌症幸存者 （CCS） 的学业成功，他们经常面临影响其学校相关功能的治疗后挑战。这项随机对照试验 （NCT03178617） 评估了 HIP 与拉丁裔家庭中较低强度、单次、常规治疗服务 （LIP） 相比的疗效。主要结局是养育效能和 CCS 的学校运作;次要结果包括育儿知识和 CCS 的学习成绩、注意力和校外功能的测量。方法 106 名儿童白血病和淋巴细胞淋巴瘤的拉丁裔幸存者 （6-12 岁） 及其父母被随机分配到 HIP （n = 54） 或 LIP （n = 52）。线性混合效应模型评估了基线、 6 个月 （T2） 和 12 个月 （T3） 评估的组别差异。结果 HIP 组的育儿效率和知识显着提高，导致在 T2 和 T3 的得分高于 LIP （P ≤ .01）。在儿童学校功能方面未发现显著的组间差异;然而，HIP 儿童在 T3 的一项注意力测量 （CPT-3 佣金） 上表现出显着更好的社会功能和表现 （P < .05）。虽然观察到 HIP 依从性挑战，只有 33 人 （61%） 完成了干预，但探索性分析表明，在充分参与的人中益处最为明显。在两个时间点，HIP 与 LIP 的满意度和感知获益均更高 （P < .05）。结论 我们的结果表明，父母主导的行为干预（如 HIP）对 CCS 及其家庭具有潜在价值。 需要进一步的研究来解决参与障碍并提高参与度，以实现利益最大化和维持。