当前位置: X-MOL 学术Br. J. Ophthalmol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Analysis of factors influencing refractive error in Fuchs eyes undergoing Descemet membrane endothelial keratoplasty triple procedure
British Journal of Ophthalmology ( IF 3.7 ) Pub Date : 2024-10-14 , DOI: 10.1136/bjo-2024-325967
Jenny Chun Ling Kuo, Kyong Jin Cho, Muhammad Ali, Albert S Jun, John G Ladas, Divya Srikumaran

Purpose To evaluate the accuracy of current intraocular lens (IOL) formulas and identify factors influencing mean error in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK) triple procedure, that is, DMEK combined with cataract extraction and IOL placement for concurrent Fuchs endothelial corneal dystrophy (FECD) and cataracts. Design Retrospective cohort study. Subjects 90 eyes with FECD undergoing uncomplicated DMEK triple procedure at Wilmer Eye Institute. Methods We analysed tomographic features of oedema, including loss of regular isopachs, displacement of the thinnest point of the cornea and the presence of posterior surface depression, and assessed the correlation with the prediction error. Main outcome measures We compared the mean error (±SD) for the Barrett Universal II (BU2), Hoffer QST, Haigis-L (HL) and Barrett True K (BTK) formulas and the percentage of eyes within 0.25, 0.5 and 1 diopter (D) of error. Results All formulas resulted in a mean hyperopic error, with the HL having the lowest mean error of 0.24 D (±0.97 D) and BU2 having the highest ME of 0.94 D (±0.97 D). For each additional tomographic feature of corneal oedema in the BU2 and Hoffer QST formulas, the mean hyperopic error increased by 0.38 D. For the BTK and HL formulas, the mean error increased by 0.35 D (p<0.001). Conclusion The number of tomographic features of oedema can be useful in identifying eyes with higher errors in IOL calculation when performing the DMEK triple procedure for FECD. All data relevant to the study are included in the article or uploaded as supplementary information.

中文翻译:


Fuchs 眼接受后弹力层内皮角膜移植术三重手术屈光不正的影响因素分析



目的 评估当前人工晶状体 (IOL) 公式的准确性,并确定影响接受后弹力层内皮角膜移植术 (DMEK) 三联手术的眼睛平均误差的因素,即 DMEK 联合白内障摘除术和 IOL 放置治疗并发 Fuchs 角膜内皮营养不良 (FECD) 和白内障。设计 回顾性队列研究。受试者 90 只患有 FECD 的眼睛在 Wilmer 眼科研究所接受简单的 DMEK 三重手术。方法 我们分析了水肿的断层扫描特征,包括规则等速线的消失、角膜最薄点的移位和后表面凹陷的存在,并评估了与预测误差的相关性。主要结局指标我们比较了 Barrett Universal II (BU2) 、Hoffer QST、Haigis-L (HL) 和 Barrett True K (BTK) 公式的平均误差 (±SD) 以及误差在 0.25、0.5 和 1 屈光度 (D) 范围内的眼睛百分比。结果 所有公式均导致平均远视误差,其中 HL 的平均误差最低,为 0.24 D (±0.97 D),BU2 的 ME 最高,为 0.94 D (±0.97 D)。对于 BU2 和 Hoffer QST 公式中角膜水肿的每个额外断层扫描特征,平均远视误差增加了 0.38 D。对于 BTK 和 HL 公式,平均误差增加了 0.35 D (p<0.001)。结论 在对 FECD 进行 DMEK 三联手术时,水肿的断层扫描特征的数量可用于识别 IOL 计算中误差较高的眼睛。与研究相关的所有数据都包含在文章中或作为补充信息上传。
更新日期:2024-10-15
down
wechat
bug