当前位置:
X-MOL 学术
›
J. Adv. Res.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-10-16 , DOI: 10.1016/j.jare.2024.10.006 Hong Qin, Anhua Xiao, Qiannan Lu, Yiyu Li, Xiaoqing Luo, Enze Zheng, Chuan Tian, Huan Liu, Xiaoya Zheng, Li Wei, Xiong Z Ruan, Ping Yang, Yaxi Chen
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-10-16 , DOI: 10.1016/j.jare.2024.10.006 Hong Qin, Anhua Xiao, Qiannan Lu, Yiyu Li, Xiaoqing Luo, Enze Zheng, Chuan Tian, Huan Liu, Xiaoya Zheng, Li Wei, Xiong Z Ruan, Ping Yang, Yaxi Chen
Metabolic regulators are key in controlling immune cell fate in the tumor microenvironment. The accumulation of tumor-associated macrophages (TAMs) in cancer greatly contributes to metastasis and poor outcome. However, the metabolic pathways responsible for TAM accumulation are largely unknown.
中文翻译:
脂肪酸受体 CD36 通过 p110γ 信号传导促进巨噬细胞浸润以刺激转移
代谢调节因子是控制肿瘤微环境中免疫细胞命运的关键。肿瘤相关巨噬细胞 (TAM) 在癌症中的积累极大地促进了转移和不良预后。然而,导致 TAM 积累的代谢途径在很大程度上是未知的。
更新日期:2024-10-16
中文翻译:
脂肪酸受体 CD36 通过 p110γ 信号传导促进巨噬细胞浸润以刺激转移
代谢调节因子是控制肿瘤微环境中免疫细胞命运的关键。肿瘤相关巨噬细胞 (TAM) 在癌症中的积累极大地促进了转移和不良预后。然而,导致 TAM 积累的代谢途径在很大程度上是未知的。