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A broad anti-anti-CRISPR strategy
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-10-15 , DOI: 10.1038/s41589-024-01743-w
Yi Zhang, Yue Feng

Prokaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study shows that CRISPR-repressed toxins defend CRISPR–Cas against anti-CRISPR proteins or RNAs by inducing abortive infection.

中文翻译:


广泛的抗 CRISPR 策略



原核生物 CRISPR-Cas 系统被噬菌体编码的抗 CRISPR 元件抵消,它们如何保护自己仍然是个谜。一项研究表明,CRISPR 抑制的毒素通过诱导流产感染来保护 CRISPR-Cas 免受抗 CRISPR 蛋白或 RNA 的侵害。
更新日期:2024-10-15
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