Migrasomes, vesicular structures discovered in migrating cells, arise from the junctions or tips of retraction fibers, and gradually grow to microscale vesicles. Migrasomes have garnered attention for their role in intercellular communication and potential therapeutic implications. This review presents an overview of recent advances in migrasome biology, covering the mechanisms of migrasome biogenesis, essential physiological roles, and their association with various diseases, alongside potential therapeutic applications. Furthermore, we share our perspectives on potential future directions in the study of migrasomes and highlight the challenges that remain in this developing area of research.

中文翻译：

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迁移体：生物发生、生理作用和治疗潜力。


迁移体是在迁移细胞中发现的囊泡结构，从回缩纤维的连接处或尖端产生，并逐渐生长为微尺度囊泡。迁移体因其在细胞间通讯中的作用和潜在的治疗意义而受到关注。本综述概述了迁移体生物学的最新进展，涵盖了迁移体生物发生的机制、基本生理作用及其与各种疾病的关联，以及潜在的治疗应用。此外，我们分享了我们对迁移体研究潜在未来方向的看法，并强调了这一发展中的研究领域仍然存在的挑战。