Two new studies have produced evidence of a prodromal phase that precedes the clinical onset of neuromyelitis optica spectrum disorder (NMOSD). In the first study, Rotstein et al. reported an increase in health-care use by patients in the 5 years leading up to a clinical diagnosis of NMOSD, and in the second study, Lee et al. found that one in seven people with NMOSD presented with neurological symptoms at least 30 days before their first attack. The ability to recognize the prodromal symptoms of NMOSD might provide opportunities for early intervention to halt disease progression.

中文翻译：

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NMOSD 前驱症状的证据

两项新研究提供了在视神经脊髓炎谱系疾病 （NMOSD） 临床发作之前存在前驱期的证据。在第一项研究中，Rotstein 等人报告了在临床诊断为 NMOSD 之前的 5 年内，患者对医疗保健的使用有所增加，在第二项研究中，Lee 等人发现，七分之一的 NMOSD 患者在首次发作前至少 30 天出现神经系统症状。识别 NMOSD 前驱症状的能力可能为早期干预以阻止疾病进展提供机会。