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B cell heterogeneity in cancer comes of age
Cancer Cell ( IF 48.8 ) Pub Date : 2024-10-14 , DOI: 10.1016/j.ccell.2024.09.013
Colleen Sturdevant, Yuliya Pylayeva-Gupta

The role of B cells in cancer remains incompletely understood. Three recent publications, including a study by Fitzsimons et al. in this issue of Cancer Cell,1 use single-cell RNA sequencing to define pan-cancer atlases of tumor-infiltrating B cell subsets, paving the way for profound advances in our understanding of B cell-dependent antitumor immunity.

中文翻译:


癌症中的 B 细胞异质性成熟



B 细胞在癌症中的作用仍不完全清楚。最近的三篇出版物,包括 Fitzsimons 等人在本期《癌细胞》上的一项研究,1 使用单细胞 RNA 测序来定义肿瘤浸润性 B 细胞亚群的泛癌图谱,为我们对 B 细胞依赖性抗肿瘤免疫的理解取得深刻进展铺平了道路。
更新日期:2024-10-14
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